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Concept IDs
RXNORM
141704
RXNORM
977428
NCI Thesaurus
C48387
RXNORM
845509
conceptId
C48387
845509
977428
141704
preferredName
Everolimus
synonym
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
description
40-O-(2-hydroxyethyl)-rapamycin
everolimus
EVEROLIMUS
Everolimus (substance)
Zortress
Product containing everolimus (medicinal product)
Everolimus-containing product
Afinitor
Everolimus
évérolimus
VANDF_CUI
4028636
NDDF_CUI
010829
ingredient of
(998191) AFINITOR 2.5 MG Oral Tablet (1310147) Afinitor DISPERZ 5mg Tablet for Suspension (1310137) Afinitor Oral Liquid Product (1172066) Afinitor Oral Product (1172067) Afinitor Pill (845518) Afinitor, 5 mg oral tablet (1310144) EVEROLIMUS 3 mg ORAL TABLET, FOR SUSPENSION [Afinitor Disperz] (845515) EVEROLIMUS 5 mg ORAL TABLET (977427) Everolimus 0.25mg Oral tablet (845512) Everolimus 10 MG Oral Tablet [AFINITOR] (845507) Everolimus 10mg Oral tablet (1310138) Everolimus 2 MG Oral Tablet for Suspension [AFINITOR DISPERZ] (1308428) Everolimus 2mg Tablet for oral suspension (845506) Everolimus Tablets (C102880) Everolimus Tablets for Oral Suspension (977434) Everolimus, 0.5 mg oral tablet (1308432) Everolimus, 5 mg oral tablet, dispersible (1163786) Product containing everolimus in oral dose form (medicinal product form) (977438) Product containing precisely everolimus 750 microgram/1 each conventional release oral tablet (clinical drug) (977431) Zortress 0.25mg Tablet (1186316) Zortress Oral Product (1186317) Zortress Pill (977436) Zortress, 0.5 mg oral tablet (2056897) Zortress, 1 mg oral tablet (977426) everolimus 0.25 MG (977429) everolimus 0.25 MG [Zortress] (977433) everolimus 0.5 MG (977435) everolimus 0.5 MG [Zortress] (977437) everolimus 0.75 MG (977440) everolimus 0.75 MG Oral Tablet [Zortress] (977439) everolimus 0.75 MG [Zortress] (2056894) everolimus 1 MG (2056895) everolimus 1 MG Oral Tablet (2056896) everolimus 1 MG [Zortress] (845505) everolimus 10 MG (845510) everolimus 10 MG [Afinitor] (1869512) everolimus 2 MG (1869515) everolimus 2 MG [Afinitor] (998188) everolimus 2.5 MG (998190) everolimus 2.5 MG [Afinitor] (998189) everolimus 2.5 mg ORAL TABLET (1869518) everolimus 3 MG (1869520) everolimus 3 MG [Afinitor] (845514) everolimus 5 MG (845517) everolimus 5 MG [Afinitor] (1119399) everolimus 7.5 MG (1119400) everolimus 7.5 MG Oral Tablet (1119402) everolimus 7.5 MG Oral Tablet [Afinitor] (1119401) everolimus 7.5 MG [Afinitor] (1308426) everolimus Oral Liquid Product (845511) everolimus Oral Tablet [Afinitor] (977430) everolimus Oral Tablet [Zortress] (1163787) everolimus Pill (1869516) everolimus Tablet for Oral Suspension [Afinitor] (1308430) everolimus@3 mg@ORAL@TABLET FOR SUSPENSION
display_845509
Afinitor
DRUGBANK_CUI
DB01590
TTY
SU
PT
IN
GN
FN
PEP
MH
BN
FSY
ET
definition
A derivative of the natural macrocyclic lactone sirolimus with immunosuppressant and anti-angiogenic properties. In cells, everolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target of Rapamycin (mTOR), a key regulatory kinase. Inhibition of mTOR activation results in the inhibition of T lymphocyte activation and proliferation associated with antigen and cytokine (IL-2, IL-4, and IL-15) stimulation and the inhibition of antibody production. (NCI05)
ATC_CUI
L01EG02
L04AA18
GS_CUI
684
MTHSPL_CUI
9HW64Q8G6G
MMSL_CUI
d05626
162489
172787
20447
269938
display_C48387
Everolimus
SNOMEDCT_US_CUI
428698007
428127005
USP_CUI
m4719
system_cui
rxnorm_977428
nci_C48387
rxnorm_845509
rxnorm_141704
prescribable
true
display_977428
Zortress
MSH_CUI
D000068338
display_141704
Everolimus
Child Concepts
(845515) EVEROLIMUS 5 mg ORAL TABLET (977438) Product containing precisely everolimus 750 microgram/1 each conventional release oral tablet (clinical drug) (845518) Afinitor, 5 mg oral tablet (1163787) everolimus Pill (1869518) everolimus 3 MG (1308428) Everolimus 2mg Tablet for oral suspension (1163786) Product containing everolimus in oral dose form (medicinal product form) (977440) everolimus 0.75 MG Oral Tablet [Zortress] (1310138) Everolimus 2 MG Oral Tablet for Suspension [AFINITOR DISPERZ] (1119402) everolimus 7.5 MG Oral Tablet [Afinitor] (1119400) everolimus 7.5 MG Oral Tablet (998188) everolimus 2.5 MG (1869512) everolimus 2 MG (1308426) everolimus Oral Liquid Product (C102880) Everolimus Tablets for Oral Suspension (977426) everolimus 0.25 MG (998189) everolimus 2.5 mg ORAL TABLET (845505) everolimus 10 MG (977427) Everolimus 0.25mg Oral tablet (845507) Everolimus 10mg Oral tablet (845506) Everolimus Tablets (998191) AFINITOR 2.5 MG Oral Tablet (1308430) everolimus@3 mg@ORAL@TABLET FOR SUSPENSION (1119399) everolimus 7.5 MG (2056894) everolimus 1 MG (1310144) EVEROLIMUS 3 mg ORAL TABLET, FOR SUSPENSION [Afinitor Disperz] (2056895) everolimus 1 MG Oral Tablet (1310147) Afinitor DISPERZ 5mg Tablet for Suspension (2056897) Zortress, 1 mg oral tablet (845512) Everolimus 10 MG Oral Tablet [AFINITOR] (977434) Everolimus, 0.5 mg oral tablet (845514) everolimus 5 MG (977437) everolimus 0.75 MG (977436) Zortress, 0.5 mg oral tablet (977431) Zortress 0.25mg Tablet (1308432) Everolimus, 5 mg oral tablet, dispersible (977433) everolimus 0.5 MG (977440) everolimus 0.75 MG Oral Tablet [Zortress] (2056896) everolimus 1 MG [Zortress] (2056897) Zortress, 1 mg oral tablet (977439) everolimus 0.75 MG [Zortress] (1186317) Zortress Pill (977429) everolimus 0.25 MG [Zortress] (1186316) Zortress Oral Product (977435) everolimus 0.5 MG [Zortress] (977436) Zortress, 0.5 mg oral tablet (977431) Zortress 0.25mg Tablet (977430) everolimus Oral Tablet [Zortress] (1869516) everolimus Tablet for Oral Suspension [Afinitor] (845518) Afinitor, 5 mg oral tablet (845517) everolimus 5 MG [Afinitor] (998191) AFINITOR 2.5 MG Oral Tablet (998190) everolimus 2.5 MG [Afinitor] (1310144) EVEROLIMUS 3 mg ORAL TABLET, FOR SUSPENSION [Afinitor Disperz] (1310147) Afinitor DISPERZ 5mg Tablet for Suspension (1310138) Everolimus 2 MG Oral Tablet for Suspension [AFINITOR DISPERZ] (1119402) everolimus 7.5 MG Oral Tablet [Afinitor] (1310137) Afinitor Oral Liquid Product (1119401) everolimus 7.5 MG [Afinitor] (845512) Everolimus 10 MG Oral Tablet [AFINITOR] (1172066) Afinitor Oral Product (845511) everolimus Oral Tablet [Afinitor] (1172067) Afinitor Pill (1869515) everolimus 2 MG [Afinitor] (1869520) everolimus 3 MG [Afinitor] (845510) everolimus 10 MG [Afinitor]
Parent Concepts