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Concept IDs
RXNORM
47858
RXNORM
225235
NCI Thesaurus
C47613
conceptId
225235
C47613
47858
preferredName
Methsuximide
synonym
1,3-Dimethyl-3-phenyl-pyrrolidin-2,5-dione
Mesuximidum
N-methyl-alpha-methyl-alpha-phenylsuccinimide
Methsuximide
mesuximid
Methsuximide-containing product
Metosuccimmide
1,3-Dimethyl-3-phenylsuccinimide
Mesuximide-containing product
METHSUXIMIDE
mesuximide
methsuximide
Celontin
1,3-Dimethyl-3-phenyl-2,5-dioxopyrrolidine
alpha-Methylphensuximide
Mesuximida
N,2-Dimethyl-2-phenylsuccinimide
N,2-dimethyl-2-phenylsuccinimide
Methsuximid
Mesuximide (substance)
Product containing mesuximide (medicinal product)
alpha-Methyl-alpha-phenyl N-methyl succinimide
(RS)-1,3-Dimethyl-3-phenyl-2,5-pyrrolidindion
Mesuximide
description
Methsuximide
mesuximide
methsuximide
Celontin
active
true
has tradename is-a
(932) ANTIEPILEPTICS (1427637) NERVOUS SYSTEM DRUGS (1431732) Succinimide derivatives
active moiety of
(207088) Celontin 300 MG Oral Capsule
VANDF_CUI
4018637
ingredient of
(211844) Celontin 150 MG Oral Capsule (207088) Celontin 300 MG Oral Capsule (1166220) Celontin Oral Product (1166221) Celontin Pill (316278) methsuximide 150 MG (199257) methsuximide 150 MG Oral Capsule (572173) methsuximide 150 MG [Celontin] (316279) methsuximide 300 MG (197949) methsuximide 300 MG Oral Capsule (567882) methsuximide 300 MG [Celontin] (372846) methsuximide Oral Capsule (366219) methsuximide Oral Capsule [Celontin] (1156726) methsuximide Oral Product (1156727) methsuximide Pill
display_47858
mesuximide
active moiety of is-a
(932) ANTIEPILEPTICS (207088) Celontin 300 MG Oral Capsule (1166220) Celontin Oral Product (1166221) Celontin Pill (1427637) NERVOUS SYSTEM DRUGS (1431732) Succinimide derivatives (197949) methsuximide 300 MG Oral Capsule (372846) methsuximide Oral Capsule (366219) methsuximide Oral Capsule [Celontin] (1156726) methsuximide Oral Product (1156727) methsuximide Pill
precise active ingredient of
(199257) methsuximide 150 MG Oral Capsule (197949) methsuximide 300 MG Oral Capsule
active ingredient of is-a
(932) ANTIEPILEPTICS (207088) Celontin 300 MG Oral Capsule (1166220) Celontin Oral Product (1166221) Celontin Pill (1427637) NERVOUS SYSTEM DRUGS (1431732) Succinimide derivatives (197949) methsuximide 300 MG Oral Capsule (372846) methsuximide Oral Capsule (366219) methsuximide Oral Capsule [Celontin] (1156726) methsuximide Oral Product (1156727) methsuximide Pill
ingredient of is-a
(932) ANTIEPILEPTICS (211844) Celontin 150 MG Oral Capsule (207088) Celontin 300 MG Oral Capsule (1166220) Celontin Oral Product (1166221) Celontin Pill (1427637) NERVOUS SYSTEM DRUGS (1431732) Succinimide derivatives (316278) methsuximide 150 MG (199257) methsuximide 150 MG Oral Capsule (572173) methsuximide 150 MG [Celontin] (316279) methsuximide 300 MG (197949) methsuximide 300 MG Oral Capsule (567882) methsuximide 300 MG [Celontin] (372846) methsuximide Oral Capsule (366219) methsuximide Oral Capsule [Celontin] (1156726) methsuximide Oral Product (1156727) methsuximide Pill
DRUGBANK_CUI
DB05246
is-a
(932) ANTIEPILEPTICS (1427637) NERVOUS SYSTEM DRUGS (1431732) Succinimide derivatives
tradename of is-a
(932) ANTIEPILEPTICS (1427637) NERVOUS SYSTEM DRUGS (1431732) Succinimide derivatives
has active ingredient is-a
(932) ANTIEPILEPTICS (1427637) NERVOUS SYSTEM DRUGS (1431732) Succinimide derivatives
TTY
IN
BN
member of
(1431732) Succinimide derivatives
basis of strength substance of
(199257) methsuximide 150 MG Oral Capsule (197949) methsuximide 300 MG Oral Capsule
definition
A succinimide with anticonvulsant properties. Although the exact mechanism of action of methsuximide is unclear, it is thought to increase the seizure threshold and suppress the paroxysmal three-cycle-per-second spike-and-wave pattern seen with absence (petit mal) seizures. The frequency of attacks is reduced by depression of nerve transmission in the motor cortex and elevation of the threshold of the CNS to convulsive stimuli, probably due to direct modification of membrane function in excitable cells and/or alteration of chemically mediated neurotransmission.
ATC_CUI
N03AD03
display_C47613
Methsuximide
MTHSPL_CUI
0G76K8X6C0
active ingredient of
(207088) Celontin 300 MG Oral Capsule (1156726) methsuximide Oral Product
precise active ingredient of is-a
(932) ANTIEPILEPTICS (1427637) NERVOUS SYSTEM DRUGS (1431732) Succinimide derivatives (199257) methsuximide 150 MG Oral Capsule (197949) methsuximide 300 MG Oral Capsule (372846) methsuximide Oral Capsule (1156726) methsuximide Oral Product (1156727) methsuximide Pill
SNOMEDCT_US_CUI
58325006
386187007
USP_CUI
m51880
system_cui
nci_C47613
rxnorm_47858
rxnorm_225235
display_225235
Celontin
prescribable
true
member of is-a
(932) ANTIEPILEPTICS (1427637) NERVOUS SYSTEM DRUGS (1431732) Succinimide derivatives
basis of strength substance of is-a
(932) ANTIEPILEPTICS (1427637) NERVOUS SYSTEM DRUGS (1431732) Succinimide derivatives (199257) methsuximide 150 MG Oral Capsule (197949) methsuximide 300 MG Oral Capsule (372846) methsuximide Oral Capsule (1156726) methsuximide Oral Product (1156727) methsuximide Pill
MSH_CUI
C100286
Child Concepts
(197949) methsuximide 300 MG Oral Capsule (199257) methsuximide 150 MG Oral Capsule (1156727) methsuximide Pill (316278) methsuximide 150 MG (372846) methsuximide Oral Capsule (1156726) methsuximide Oral Product (316279) methsuximide 300 MG (1166221) Celontin Pill (1166220) Celontin Oral Product (572173) methsuximide 150 MG [Celontin] (207088) Celontin 300 MG Oral Capsule (211844) Celontin 150 MG Oral Capsule (366219) methsuximide Oral Capsule [Celontin] (567882) methsuximide 300 MG [Celontin]
Parent Concepts
(C264) Anticonvulsant Agent (1431732) Succinimide derivatives