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Concept IDs
RXNORM
4448
NCI Thesaurus
C80591
conceptId
C80591
4448
preferredName
Flucloxacillin
synonym
Flucloxacillin
3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillin
flucloxacillin
Floxacillin
Flucloxacillin-containing product
(2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
description
Flucloxacillinum
Flucloxacillin
Flucloxacilline
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))-
floxacillin
Floxacillin
flucloxacillin
Fluorochloroxacillin
Floxacillin-containing product
Flucloxacillin (substance)
Product containing flucloxacillin (medicinal product)
Flucloxacilina
part of
(1008111) amoxicillin / floxacillin (1007586) ampicillin / floxacillin
NDDF_CUI
003516
ingredient of
(1160228) Floxacillin-containing product in parenteral dose form (1153185) Product containing ampicillin and flucloxacillin in oral dose form (medicinal product form) (1160230) Product containing flucloxacillin in oral dose form (medicinal product form) (370886) amoxicillin / floxacillin Oral Capsule (1152880) amoxicillin / floxacillin Oral Liquid Product (1152881) amoxicillin / floxacillin Oral Product (757162) amoxicillin / floxacillin Oral Solution (370887) amoxicillin / floxacillin Oral Suspension (1152882) amoxicillin / floxacillin Pill (1153183) ampicillin / floxacillin Injectable Product (378107) ampicillin / floxacillin Injectable Solution (370909) ampicillin / floxacillin Oral Capsule (1153184) ampicillin / floxacillin Oral Liquid Product (757326) ampicillin / floxacillin Oral Solution (1153186) ampicillin / floxacillin Pill (439642) floxacillin 10 MG/ML (346420) floxacillin 167 MG/ML (439639) floxacillin 20 MG/ML (331062) floxacillin 25 MG/ML (331061) floxacillin 250 MG (346421) floxacillin 250 MG/ML (439641) floxacillin 28.6 MG/ML (346427) floxacillin 400 MG/ML (439640) floxacillin 5 MG/ML (331949) floxacillin 50 MG/ML (331950) floxacillin 500 MG (378106) floxacillin Injectable Solution (372206) floxacillin Oral Capsule (1160229) floxacillin Oral Liquid Product (756864) floxacillin Oral Solution (372205) floxacillin Oral Suspension (375071) floxacillin Oral Tablet (1160231) floxacillin Pill
display_4448
Floxacillin
display_C80591
Flucloxacillin
DRUGBANK_CUI
DB00301
(2625) Cloxacillin
TTY
N1
PT
IN
FN
MH
FSY
ET
definition
A narrow-spectrum, semisynthetic isoxazolyl penicillin with antibacterial activity. Floxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.
member of
(1431530) Beta-lactamase resistant penicillins
basis of strength substance of
(2566977) Ampicillin 25 mg/mL and floxacillin (as floxacillin magnesium) 25 mg/mL oral suspension (247684) Floxacillin (as floxacillin magnesium) 25 mg/mL oral suspension (2608840) Floxacillin (as floxacillin sodium) 2 g powder for solution for infusion and/or injection vial (105099) Floxacillin (as floxacillin sodium) 250 mg powder for solution for injection vial (755759) Floxacillin (as floxacillin sodium) 50 mg/mL oral solution (2197239) Product containing precisely ampicillin (as ampicillin sodium) 250 milligram and flucloxacillin (as flucloxacillin sodium) 250 milligram/1 vial powder for conventional release solution for injection (clinical drug) (250463) ampicillin 250 MG / floxacillin 250 MG Oral Capsule (199468) floxacillin 250 MG Oral Capsule (105100) floxacillin 250 MG/ML Injectable Solution (105101) floxacillin 400 MG/ML Injectable Solution (247647) floxacillin 50 MG/ML Oral Suspension (199469) floxacillin 500 MG Oral Capsule
ATC_CUI
J01CF05
active ingredient of
(2111662) Ampicillin and floxacillin only product (2113435) Floxacillin only product (2113437) Floxacillin only product in parenteral dose form (1160228) Floxacillin-containing product in parenteral dose form (1153185) Product containing ampicillin and flucloxacillin in oral dose form (medicinal product form) (1160230) Product containing flucloxacillin in oral dose form (medicinal product form) (2111663) Product containing only ampicillin and flucloxacillin in oral dose form (medicinal product form) (2111664) Product containing only ampicillin and flucloxacillin in parenteral dose form (medicinal product form) (2113436) Product containing only flucloxacillin in oral dose form (medicinal product form) (1007586) ampicillin / floxacillin (1153183) ampicillin / floxacillin Injectable Product
has tradename
(142129) Floxapen (151777) Floxapen Forte (225803) Fluclomix 250 (225804) Fluclomix 500 (153558) Flucloxin (128782) Ladropen (152382) Stafoxil (152758) Zoxin
SNOMEDCT_US_CUI
387544009
96067005
has modification
(235825) floxacillin magnesium (235750) floxacillin sodium
system_cui
rxnorm_4448
nci_C80591
has form
(235825) floxacillin magnesium (235750) floxacillin sodium (1309402) floxacillin sodium monohydrate
MSH_CUI
D005436
Child Concepts
(152382) Stafoxil (756864) floxacillin Oral Solution (1153186) ampicillin / floxacillin Pill (1153185) Product containing ampicillin and flucloxacillin in oral dose form (medicinal product form) (1160231) floxacillin Pill (153558) Flucloxin (378106) floxacillin Injectable Solution (1160230) Product containing flucloxacillin in oral dose form (medicinal product form) (225804) Fluclomix 500 (372205) floxacillin Oral Suspension (378107) ampicillin / floxacillin Injectable Solution (225803) Fluclomix 250 (370886) amoxicillin / floxacillin Oral Capsule (331950) floxacillin 500 MG (370887) amoxicillin / floxacillin Oral Suspension (372206) floxacillin Oral Capsule (370909) ampicillin / floxacillin Oral Capsule (152758) Zoxin (331061) floxacillin 250 MG (331062) floxacillin 25 MG/ML (346427) floxacillin 400 MG/ML (1153184) ampicillin / floxacillin Oral Liquid Product (1153183) ampicillin / floxacillin Injectable Product (346420) floxacillin 167 MG/ML (1160228) Floxacillin-containing product in parenteral dose form (331949) floxacillin 50 MG/ML (757326) ampicillin / floxacillin Oral Solution (1160229) floxacillin Oral Liquid Product (128782) Ladropen (1152880) amoxicillin / floxacillin Oral Liquid Product (346421) floxacillin 250 MG/ML (1152882) amoxicillin / floxacillin Pill (1152881) amoxicillin / floxacillin Oral Product (439639) floxacillin 20 MG/ML (757162) amoxicillin / floxacillin Oral Solution (151777) Floxapen Forte (142129) Floxapen (439641) floxacillin 28.6 MG/ML (439640) floxacillin 5 MG/ML (375071) floxacillin Oral Tablet (439642) floxacillin 10 MG/ML
Parent Concepts
(1431530) Beta-lactamase resistant penicillins (C1500) Penicillin Antibiotic