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Concept IDs
RXNORM
4448
NCI Thesaurus
C80591
conceptId
C80591
4448
preferredName
Flucloxacillin
synonym
Flucloxacillin
3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillin
flucloxacillin
Floxacillin
Flucloxacillin-containing product
(2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
description
Flucloxacillinum
Flucloxacillin
Flucloxacilline
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))-
floxacillin
Floxacillin
flucloxacillin
Fluorochloroxacillin
Floxacillin-containing product
Flucloxacillin (substance)
Product containing flucloxacillin (medicinal product)
Flucloxacilina
NDDF_CUI
003516
display_4448
Floxacillin
display_C80591
Flucloxacillin
DRUGBANK_CUI
DB00301
TTY
N1
PT
IN
FN
MH
FSY
ET
definition
A narrow-spectrum, semisynthetic isoxazolyl penicillin with antibacterial activity. Floxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.
ATC_CUI
J01CF05
SNOMEDCT_US_CUI
387544009
96067005
system_cui
rxnorm_4448
nci_C80591
MSH_CUI
D005436
Child Concepts
(152382) Stafoxil (756864) floxacillin Oral Solution (1153186) ampicillin / floxacillin Pill (1153185) Product containing ampicillin and flucloxacillin in oral dose form (medicinal product form) (1160231) floxacillin Pill (153558) Flucloxin (378106) floxacillin Injectable Solution (1160230) Product containing flucloxacillin in oral dose form (medicinal product form) (225804) Fluclomix 500 (372205) floxacillin Oral Suspension (378107) ampicillin / floxacillin Injectable Solution (225803) Fluclomix 250 (370886) amoxicillin / floxacillin Oral Capsule (331950) floxacillin 500 MG (370887) amoxicillin / floxacillin Oral Suspension (372206) floxacillin Oral Capsule (370909) ampicillin / floxacillin Oral Capsule (152758) Zoxin (331061) floxacillin 250 MG (331062) floxacillin 25 MG/ML (346427) floxacillin 400 MG/ML (1153184) ampicillin / floxacillin Oral Liquid Product (1153183) ampicillin / floxacillin Injectable Product (346420) floxacillin 167 MG/ML (1160228) Floxacillin-containing product in parenteral dose form (331949) floxacillin 50 MG/ML (757326) ampicillin / floxacillin Oral Solution (1160229) floxacillin Oral Liquid Product (128782) Ladropen (1152880) amoxicillin / floxacillin Oral Liquid Product (346421) floxacillin 250 MG/ML (1152882) amoxicillin / floxacillin Pill (1152881) amoxicillin / floxacillin Oral Product (439639) floxacillin 20 MG/ML (757162) amoxicillin / floxacillin Oral Solution (151777) Floxapen Forte (142129) Floxapen (439641) floxacillin 28.6 MG/ML (439640) floxacillin 5 MG/ML (375071) floxacillin Oral Tablet (439642) floxacillin 10 MG/ML
Parent Concepts