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Concept IDs
RXNORM
235524
NCI Thesaurus
C61436
RXNORM
42769
conceptId
42769
235524
C61436
preferredName
Licorice
synonym
Glycyrrhiza Glabra Root
Glycyrrhiza glabra root extract
Glycyrrhiza Glabra (Licorice) Rhizome/root
Glycyrrhiza Glabra Root With Rhizome
Yashtimadhu Root
Glycyrrhiza Glabra (Licorice) Root
Glycyrrhiza Glabra (Licorice) Rhizome/root Extract
Glycyrrhiza Violacea Root
Glycyrrhiza Glabra (Licorice) Root Extract
Liquorice
Glycyrrhiza Pallida Root
Cultivated Licorice Root
Liquorice Root (Glycyrrhiza Glabra)
Spanish Licorice Root
Glycyrrhiza Glandulifera Root
Glycyrrhiza Glabra Processed Root
Glycyrrhiza Hirsuta Root
Licorice Rhizome/root Extract
Glycyrrhizia
Russian Licorice Root
Guang Guo Gan Cao Root
Gan Cao Root
Liquiritiae Radix
Prepared Liauorice Root (Glycyrrhiza Glabra)
Turkish Licorice Root
Liquorice-containing product
description
glycyrrhiza syrup (obsolete)
GLYCYRRHIZA
Product containing Glycyrrhiza (medicinal product)
Chinese licorice
Licorice
GLYCYRRHIZA EXTRACT
licorice
Licorice Root
LICORICE
licorice root extract
Licorice (substance)
Licorice-containing product
licorice root
GS_CUI
5116
MTHSPL_CUI
61ZBX54883
VANDF_CUI
4019085
4019133
4023415
NDDF_CUI
002421
008129
008156
002490
002491
display_42769
licorice
MMSL_CUI
NOCODE
d04424
SNOMEDCT_US_CUI
31347007
317272008
DRUGBANK_CUI
DB14312
DB10675
system_cui
nci_C61436
rxnorm_42769
rxnorm_235524
prescribable
true
TTY
SU
PT
IN
MS
GN
FN
definition
An herbal extract derived from the root of the plant Glycyrrhiza glabra with potential anti-inflammatory, antioxidant, and antineoplastic activities. Licorice root extract contains glycoside glycyrrhizinic acid and numerous flavonoids. Glycyrrhizinic acid in licorice root extract is hydrolyzed to glycyrrhetic acid (GA); GA inhibits 11 beta-hydroxysteroid dehydrogenase, resulting in inhibition of the conversion of cortisol to the inactive steroid cortisone and elevated cortisol levels. In addition, GA inhibits 17,20-lyase and 17 beta-hydroxysteroid dehydrogenase, resulting in decreased conversions of 17-hydroxyprogesterone to androstenedione and androstenedione to testosterone. The primary antioxidant found in licorice root, the flavonoid glabridin, may inactivate or inhibit the activities of some cytochrome P450 enzymes. In tumor cells, beta-hydroxy-DHP, another flavonoid, may induce Bcl-2 phosphorylation, apoptosis, and G2/M cell cycle arrest.
display_235524
licorice root
display_C61436
Licorice
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